ABSTRACT
Objective:To study the characteristics,related factors and precautionary measures of ceftriaxone-induced anaphylactic shock,and provide reference for clinical safe medication.Method:The literature between January, 1994 and December,2007 was collected from Chinese Journal Full-text Database,Chinese Science and Technology Journal Full-text Database,and Wanfang Medicine Data China info,70 cases with ceftriaxone-induced anaphylactic shock were reviewed and analyzed.Result:Of the 70 cases,43(61.4%) were male,and 27(38.6%) were female.64(91.4%) received intravenous fusion or intravenous injection and 6(8.6%),intramuscular or prostate capsule injection.Most of the anaphylactic shock cases occurred within 20 minutes(71.2%) after administration.61 cases recovered(87.1%) and 8 cases died(11.4%) and 1 cases became vegetable(1.5%) after treatment.Conclusion:The ceftriaxone-induced anaphylactic shock is rapid so as to be timely rescued.Patients should be asked about their case history and medication history in detail before treatment in order to reduce occurrences of shock.
ABSTRACT
Objective:To analyze adverse drug reactions(ADRs)associated with proprietary Chinese medicine occurring in Beijing Hospital.Method:The ADRs associated with proprietary Chinese medicine between 2002 and 2006 were collected and the associated information was retrospectively analyzed.Result:a total of 179 ADRs were analyzed. Most of them occurring in women patients(76.1%)with hyperplasia of mammary glands who took Xiaojin pills and Xi- huang pills(22.1% & 12%).The herbal medicine injections were the other most associated ones.The clinical appearances of ADRs were rash and bodily manifestation of hypersensitiveness.Condusion:The investigation of Chinese medicine ADR plays a very important role in the modernization of Chinese medicine.
ABSTRACT
Objective:To analyze the occurrence information and clinical manifestations of adverse reactions caused by quinolones antimicrobial drugs in Beijing Hospital and to provide the basis for clinical use.Method:In a retrospective study,128 cases of adverse reactions caused by quinolones antimicrobial drugs from 2003 to 2007 in Beijing Hospital were statistically analyzed in respect of drug categories,genders,ages,routes of administration,organs or systems, clinical manifestations,etc.Result:The drugs causing adverse drug reactions included seven categories.Levofloxacin showed the highest propotion,and intravenous drip was the main route of administration,and damages of skin were the most common manifestation.Conclusion:Adverse reactions monitoring of anti-infective agents should be strengthened to ensure the rational and safe patient medication.
ABSTRACT
The pharmacological effects and clinical applications of fish oil preparations were reviewed. Fish oil is a natural material. Its excellent clinical tolerance and multiple pharmacological activities make it a pharmaceutical of broad prospects. Fish oil preparations have been used in the therapy and prevention of hyperlipidemia and atherosclerosis in diabetics. They have also been proved effective in improving symptoms of burns and abscesses. Additionally,fish oil preparations can replace non-steroidal anti-inflammatory drugs in the therapy of immune system disorders and have effects of slowering aging and improving the memory faculty of the aged. Applications of fish oil in organ transplantation have also been reported.